N-(5-氨基戊基)-5-(二甲基氨基)萘-1-磺酰胺

N-(5-氨基戊基)-5-(二甲基氨基)萘-1-磺酰胺化学性质

熔点 :137-140 °C
沸点 :505.5±60.0 °C(Predicted)
密度 :1.190±0.06 g/cm3(Predicted)
储存条件 :−20°C
酸度系数(pKa) :11.96±0.50(Predicted)
形态 :powder
颜色 :Yellow to yellowish green
最大波长(λmax) :335 nm
BRN :2951070
稳定性 :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20°C for up to 1 month.
生物领域应用 :Measuring cardiac autophagic flux; treating cataract,fibrosis,Parkinson’s disease,peritoneal ovarian tumor dissemination,respiratory diseases,lung diseases,Huntington’s disease,spinobulbar atrophy,spinocerebellar ataxia,denta

安全信息

N-(5-氨基戊基)-5-(二甲基氨基)萘-1-磺酰胺性质、用途与生产工艺

生物活性 Dansylcadaverine (Monodansyl cadaverine) 是一种用于标记自噬空泡的自荧光化合物。Dansylcadaverine 是谷氨酰胺转胺酶的高亲和力底物，能阻断受体介导的多种配体的内吞作用。
体外研究

The inhibitory activity of dansylcadaverine reflects its ability to serve as a substrate for transglutaminases and to block competitively the crosslinking of fibrin molecules.
Dansylcadaverine, a cationic fluorescent probe binds to bacterial lipopolysaccharide and lipid A, and is displaced competitively by other compounds which possess affinity toward endotoxins.

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