ChemicalBook CAS数据库列表 7-丁基-6-(4-羟基苯基)-5H-吡咯并[2,3-B]吡嗪
7-丁基-6-(4-羟基苯基)-5H-吡咯并[2,3-B]吡嗪
![7-丁基-6-(4-羟基苯基)-5H-吡咯并[2,3-B]吡嗪,496864-16-5,结构式](https://www.chemicalbook.com/CAS/GIF/496864-16-5.gif)
- CAS号:496864-16-5
- 英文名:RP107
- 中文名:7-丁基-6-(4-羟基苯基)-5H-吡咯并[2,3-B]吡嗪
- CBNumber:CB4265483
- 分子式:C16H17N3O
- 分子量:267.33
- MOL File:496864-16-5.mol
7-丁基-6-(4-羟基苯基)-5H-吡咯并[2,3-B]吡嗪化学性质
- 熔点 :281-283°C
- 密度 :1.227
- 储存条件 :Keep in dark place,Sealed in dry,2-8°C
- 溶解度 :DMSO (Slightly), Methanol (Slightly)
- 形态 :Yellow solid
- 酸度系数(pKa) :9.67±0.15(Predicted)
- 颜色 :Light Orangish Yellow
安全信息
7-丁基-6-(4-羟基苯基)-5H-吡咯并[2,3-B]吡嗪性质、用途与生产工艺
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用途
A cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of cyclin dependent kinases (Cdks: IC50 =150nM, 120 nM, 400 nM and 200 nM for Cdk 1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk5/p25, respectively). Also inhibits the activity of clycogen synthase kinase-3 (GSK-3,:(IC50 =500 nM and 1.5 uM for GSK-3a, GSK-3β, respectively), and c-Jun N-terminal kinase (JNK: IC50 approx. 3-10uM).
7-丁基-6-(4-羟基苯基)-5H-吡咯并[2,3-B]吡嗪上下游产品信息
上游原料
下游产品
7-丁基-6-(4-羟基苯基)-5H-吡咯并[2,3-B]吡嗪生产厂家
- 公司名称：ALEXIS
- 联系电话：--
- 电子邮件：alexis-ch@alexis-corp.ch
- 国家：瑞士
- 产品数：3599
- 优势度：74
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