ChemicalBook CAS数据库列表 ASOXIME CHLORIDE
ASOXIME CHLORIDE
- CAS号:34433-31-3
- 英文名:ASOXIME CHLORIDE
- 中文名:ASOXIME CHLORIDE
- CBNumber:CB4137803
- 分子式:C14H16Cl2N4O3
- 分子量:359.21
- MOL File:34433-31-3.mol
ASOXIME CHLORIDE化学性质
- 熔点 :145-147°C
- 储存条件 :-20°C
- 溶解度 :H2O: soluble15mg/mL (clear solution)
- 形态 :powder
- 颜色 :white to beige
- 稳定性 :1-10% Aqueous solution
安全信息
- WGK Germany :3
ASOXIME CHLORIDE性质、用途与生产工艺
- 生物活性 Asoxime dichloride 是乙酰胆碱受体 (AChRs) 拮抗剂，包括烟碱受体，α7 乙酰胆碱受体。Asoxime dichloride 参与调节免疫应答。Asoxime dichloride 可作为抗原使用，改善神经系统的免疫效果。
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靶点
IC50: acetylcholine receptors (AChRs)
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体内研究
Asoxime dichloride (intramuscular injection into the rear limb; 2% and 0.2% of median lethal dose 15.6 and 1.56 mg/kg; 21 or 65 days) significantly improved vaccination efficacy as a dose-dependent manner when KLH is 1 mg/kg. A combination of HI-6 and keyhole limpet hemocyanin (KLH) produces a vaccination of almost the same efficacy as that for Freund's complete adjuvant.
Animal Model: Balb/c mice Dosage: 2% and 0.2% of median lethal dose 15.6 and 1.56mg/kg Administration: Intramuscular injection into the rear limb Result: Improved vaccination efficacy at the level of immunity regulation by the nervous system.
ASOXIME CHLORIDE上下游产品信息
上游原料
下游产品
ASOXIME CHLORIDE生产厂家
- 公司名称：CHEMICAL LAND21
- 联系电话：--
- 电子邮件：sales21@chemicalland21.com
- 国家：韩国
- 产品数：6315
- 优势度：74
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