ChemicalBook CAS数据库列表 TERTATOLOL
TERTATOLOL
- CAS号:83688-84-0
- 英文名:1-(tert-butylamino)-3-[(3,4-dihydro-2H-1-benzothiopyran-8-yl)oxy]propan-2-ol
- 中文名:TERTATOLOL
- CBNumber:CB3920200
- 分子式:C16H25NO2S
- 分子量:295.4402
- MOL File:83688-84-0.mol
TERTATOLOL化学性质
- 熔点 :70-72 °C
- 沸点 :465.0±45.0 °C(Predicted)
- 密度 :1.112±0.06 g/cm3(Predicted)
- 储存条件 :Store at -20°C
- 溶解度 :Soluble in DMSO
- 酸度系数(pKa) :13.84±0.20(Predicted)
TERTATOLOL性质、用途与生产工艺
- 生物活性 Tertatolol 是一种有效的 beta-adrenoceptor 和 5-HT receptor 拮抗剂，具有舒张血管的作用。
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体外研究
In serum-free media, tertatolol does not significantly alter the incorporation of 3 H-thymidine after 28 h of incubation in human mesangial cell (HMC). In the presence of 1% serum, tertatolol significantly reduces 3 H-thymidine incorporation. Tertatolol also inhibits 3 H incorporation when PDGF and thrombin are used as the stimulus. Tertatolol inhibits the reduction in planar surface area of HMC induced by angiotensin II. The inhibitory effect of tertatolol on HMC proliferation is also potentiated by ritanserin and MDL 72222, 5HT2 and 5HT3 antagonists, respectively.
TERTATOLOL上下游产品信息
上游原料
下游产品
TERTATOLOL生产厂家
- 公司名称：TORONTO
- 联系电话：--
- 电子邮件：info@trc-canada.com
- 国家：加拿大
- 产品数：6038
- 优势度：71
