Γ-(P-硝基苯胺)-L-谷氨酸盐酸盐

Γ-(P-硝基苯胺)-L-谷氨酸盐酸盐化学性质

储存条件 :2-8°C
溶解度 :Soluble in Water (up to 5 mg/ml).
形态 :solid
颜色 :Off-white
稳定性 :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
EPA化学物质信息 :L-Glutamine, N-(4-nitrophenyl)-, monohydrochloride (67953-08-6)

安全信息

Γ-(P-硝基苯胺)-L-谷氨酸盐酸盐性质、用途与生产工艺

生物活性 GPNA (L-γ-Glutamyl-p-nitroanilide)是一种有效的谷氨酰胺 (Gln) 转运蛋白ASCT2(SLC1A5) 的选择性抑制剂，Ki为55 µM。
靶点
Target Value
ASCT2
(Cell-free assay) 55 μM(Ki)

体外研究

GPNA (10-1000 μM; 48 hours) induces a dose-dependent decrease of cell viability in A549 cells.

Cell Viability Assay

Cell Line:	A549 cells
Concentration:	10, 100, 250, 500 , and 1000 μM
Incubation Time:	48 hours
Result:	Induced a dose-dependent decrease of cell viability, with an IC50 roughly corresponding to ~250 μM.

Γ-(P-硝基苯胺)-L-谷氨酸盐酸盐上下游产品信息

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Γ-(P-硝基苯胺)-L-谷氨酸盐酸盐生产厂家

67953-08-6, Γ-(P-硝基苯胺)-L-谷氨酸盐酸盐相关搜索:

Target	Value
ASCT2 (Cell-free assay)	55 μM(Ki)