生物活性 靶点 体外研究 体内研究 LM 22A4 试剂级价格
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LM 22A4

LM 22A4,37988-18-4,结构式
LM 22A4
  • CAS号:37988-18-4
  • 英文名:LM 22A4
  • 中文名:LM 22A4
  • CBNumber:CB32682689
  • 分子式:C15H21N3O6
  • 分子量:339.34
  • MOL File:37988-18-4.mol
LM 22A4化学性质
  • 储存条件 :2-8°C
  • 溶解度 :H2O: soluble2mg/mL, clear (warmed)
  • 形态 :powder
  • 颜色 :white to beige
  • 稳定性 :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
安全信息
  • WGK Germany :3

LM 22A4性质、用途与生产工艺

  • 生物活性 LM22A-4 (LM 22A4) 是一种的 tyrosine kinase receptor B (TrkB) 的激动剂,可减少与脊髓损伤相关的组织损伤的发展。
  • 靶点
    TargetValue
    TrkB
    ()
  • 体外研究

    LM22A-4 significantly up-regulates OPN and ALPase mRNA expression in a dose-dependent manner and OC mRNA level is significantly increased by 5 μM of LM22A-4. LM22A-4 significantly increases OPN, ALPase and OC mRNA expression in a time-dependent manner. LM22A-4 stimulated OPN and OC mRNA expression in HCEM cells cultured with mineralizing media.

  • 体内研究

    LM22A-4 (10 mg/kg, i.p.) significantly reduces the degree of tissue injury and apoptosis (TUNEL staining and caspase-3 and Bcl-2 expression) compared with vehicle treated group. LM22A-4 also significantly ameliorates the recovery of limb function. LM22A-4 (10 mg/kg) treatment results in a significant increase in neuron number. LM22A-4 administration (10 mg/kg) significantly improves the neurological scores compared with those of the solvent-treated animals.

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LM 22A4 试剂级价格
  • 更新日期:2024/11/08
  • 产品编号:HY-100673
  • 产品名称:LM22A-4
  • CAS编号:
  • 包装:1 mg
  • 价格:240元
  • 更新日期:2024/11/08
  • 产品编号:HY-100673
  • 产品名称:LM 22A4 LM22A-4
  • CAS编号:37988-18-4
  • 包装:5mg
  • 价格:600元
LM 22A4生产厂家
  • 公司名称:北京百灵威科技有限公司
  • 联系电话:010-82848833 400-666-7788
  • 电子邮件:jkinfo@jkchemical.com
  • 国家:中国
  • 产品数:96815
  • 优势度:76
  • 公司名称:上海超岚化工科技中心
  • 联系电话:021-QQ:65489617 15618227136
  • 电子邮件:Sales@ATKchemical.com
  • 国家:中国
  • 产品数:7267
  • 优势度:58
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