ChemicalBook CAS数据库列表 S-[(1E)-1;2-DICHLOROETHENYL]--L-CYSTEINE
S-[(1E)-1;2-DICHLOROETHENYL]--L-CYSTEINE
![S-[(1E)-1;2-DICHLOROETHENYL]--L-CYSTEINE,13419-46-0,结构式](https://www.chemicalbook.com/CAS/GIF/13419-46-0.gif)
- CAS号:13419-46-0
- 英文名:S-(E-1,2-DICHLOROVINYL)-L-CYSTEINE
- 中文名:S-[(1E)-1;2-DICHLOROETHENYL]--L-CYSTEINE
- CBNumber:CB31422082
- 分子式:C5H7Cl2NO2S
- 分子量:216.09
- MOL File:13419-46-0.mol
S-[(1E)-1;2-DICHLOROETHENYL]--L-CYSTEINE化学性质
- 熔点 :155-156 °C (decomp)
- 沸点 :339.7±42.0 °C(Predicted)
- 密度 :1.437 (estimate)
- 折射率 :1.6100 (estimate)
- 储存条件 :Store at -20°C
- 溶解度 :DMSO : 23 mg/mL (106.44 mM);Water : 1.034 mg/mL (4.79 mM)
- 形态 :Solid
- 酸度系数(pKa) :2.01±0.10(Predicted)
- 颜色 :White to off-white
S-[(1E)-1;2-DICHLOROETHENYL]--L-CYSTEINE性质、用途与生产工艺
- 生物活性 DCVC (S-[(1E)-1,2-dichloroethenyl]--L-cysteine) 是一种三氯乙烯 (TCE) 的生物活性代谢产物。DCVC 可抑制病原体刺激的组织培养物中促炎细胞因子 IL-1β，IL-8 和 TNF-α 的释放。
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体外研究
Extraplacental membranes are cultured for 4, 8, and 24h with the trichloroethylene (TCE) metabolite S-(1,2-dichlorovinyl)-l-cysteine (DCVC) in the absence or presence of lipoteichoic acid (LTA) or lipopolysaccharide (LPS) to simulate infection. In addition, membranes were cocultured with DCVC and Group B Streptococcus (GBS). DCVC (5-50μM) significantly inhibited LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4h. DCVC inhibits pathogen-stimulated cytokine (IL-1β, IL-8, and TNF-α) release in a concentration-dependent manner.
S-[(1E)-1;2-DICHLOROETHENYL]--L-CYSTEINE上下游产品信息
上游原料
下游产品
S-[(1E)-1;2-DICHLOROETHENYL]--L-CYSTEINE生产厂家
- 公司名称：CHEMICAL LAND21
- 联系电话：--
- 电子邮件：sales21@chemicalland21.com
- 国家：韩国
- 产品数：6303
- 优势度：74
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