ChemicalBook CAS数据库列表 西他苯
西他苯
- CAS号:55986-43-1
- 英文名:CETABEN
- 中文名:西他苯
- CBNumber:CB2752657
- 分子式:C23H39NO2
- 分子量:361.56
- MOL File:55986-43-1.mol
西他苯化学性质
- 沸点 :503.4±33.0 °C(Predicted)
- 密度 :0.979±0.06 g/cm3(Predicted)
- 储存条件 :Store at -20°C
- 溶解度 :≤1mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
- 形态 :crystalline solid
- 酸度系数(pKa) :4.76±0.10(Predicted)
- 颜色 :White to off-white
西他苯性质、用途与生产工艺
- 生物活性 Cetaben 是一种不依赖 PPARα 的过氧化物酶体增殖物。Cetaben 是一种非纤维化降血脂药，可有效降低胆固醇和甘油三酸酯的浓度。
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体外研究
Cetaben (10 µM; 24 hours) induces severe micromorphological and ultrastructural changes in HepG2 and MH1C1 cells. After treatment with 100 µM cetaben, cells contained several Golgi regions, most of them disintegrated into vesicles.
Cetaben-treated (10 µM; 24 hours) cells were characterized by a striking heterogeneity of the peroxisomal population with the occurrence of dumbbell-shaped and cup-shaped peroxisomal profiles in MH1C1cells.
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体内研究
Cetaben reveales a significant rise in the activities of peroxisomal enzymes in both the liver and kidney at doses of 50-100 mg/kg body over 10 days, but the maximal effect is observed at 250 mg/kg.
Animal Model: Male Wistar rats Dosage: 10,25,50,100,250 and 500 mg/kg Administration: Gavage; 10 day Result: Revealed a significant rise in the activities of peroxisomal enzymes in both the liver and kidney at doses of 50-100 mg/kg body over 10 days, but the maximal effect was observed at 250 mg/kg.
西他苯上下游产品信息
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西他苯 试剂级价格
- 更新日期：2024/11/08
- 产品编号：HY-119964
- 产品名称：西他苯 Cetaben
- CAS编号：55986-43-1
- 包装：5mg
- 价格：500元
- 更新日期：2024/11/08
- 产品编号：HY-119964
- 产品名称：西他苯 Cetaben
- CAS编号：55986-43-1
- 包装：10mM * 1mLin DMSO
- 价格：550元
西他苯生产厂家
- 公司名称：Leancare Ltd.
- 联系电话：--
- 电子邮件：enquiry@leancare.co.uk
- 国家：英国
- 产品数：6446
- 优势度：42
- 公司名称：Carbone Scientific CO., LTD
- 联系电话：--
- 电子邮件：sales@carbonesci.com
- 国家：英国
- 产品数：6666
- 优势度：30
- 公司名称：UK GREEN SCIENTIFIC CO.,LIMITED
- 联系电话：--
- 电子邮件：sales@gs-chem.com
- 国家：英国
- 产品数：6098
- 优势度：47
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