ChemicalBook CAS数据库列表 Terlipressin Diacetate Salt
Terlipressin Diacetate Salt
- CAS号:1884420-36-3
- 英文名:Terlipressin Diacetate Salt
- 中文名:Terlipressin Diacetate Salt
- CBNumber:CB24806497
- 分子式:C54H78N16O17S2
- 分子量:1287.43
- MOL File:1884420-36-3.mol
Terlipressin Diacetate Salt化学性质
- 溶解度 :DMSO (Slightly), Methanol (Slightly)
- 形态 :Solid
- 颜色 :White
Terlipressin Diacetate Salt性质、用途与生产工艺
- 生物活性 Terlipressin acetate 是一种具有血管活性的加压素类似物,也是一种高度选择性的加压素 V1 受体激动剂,可减少内脏血流量和门脉压力并控制急性静脉曲张破裂出血。Terlipressin acetate 具有抗炎和抗氧化作用,可用于肝肾综合征和耐去甲肾上腺素的败血性休克的研究。
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靶点
Vasopressin V1 receptor
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体外研究
Terlipressin (25 nM; 24-72 hours; IEC-6 cells) treatment significantly improves cell viability, proliferation and apoptosis in IEC-6 cells.
Terlipressin inhibits the secretion of TNF-α and 15-F2t-isoprostane from IEC-6 cells following oxygen and glucose deprivation/re-oxygenation (OGD/R). Terlipressin administration following OGD attenuates OGD/R-induced cell damage via the PI3K signaling pathway.Cell Proliferation Assay
Cell Line: IEC-6 cells induced by oxygen and glucose deprivation/re-oxygenation (OGD/R) Concentration: 25 nM Incubation Time: 24 hours, 48 hours, 72 hours Result: Significantly increased the proliferation of IEC-6 cells. -
体内研究
Using a mouse nonlethal hepatic ischemia-reperfusion (IR) model, Terlipressin administration significantly ameliorates IR-induced liver apoptosis, necrosis and inflammation.
Terlipressin Diacetate Salt上下游产品信息
上游原料
下游产品
Terlipressin Diacetate Salt 试剂级价格
- 更新日期:2024/04/30
- 产品编号:HY-12554A
- 产品名称:Terlipressin diacetate
- CAS编号:
- 包装:5 mg
- 价格:500元
- 更新日期:2024/04/30
- 产品编号:HY-12554A
- 产品名称:Terlipressin diacetate
- CAS编号:
- 包装:25 mg
- 价格:1250元
Terlipressin Diacetate Salt生产厂家
- 公司名称:TargetMol Chemicals Inc.
- 联系电话:+1-781-999-5354 +1-00000000000
- 电子邮件:marketing@targetmol.com
- 国家:美国
- 产品数:19892
- 优势度:58
- 公司名称:MedChemExpress
- 联系电话:--
- 电子邮件:sales@medchemexpress.com
- 国家:美国
- 产品数:6398
- 优势度:58