ChemicalBook CAS数据库列表 呋喃茶碱
呋喃茶碱
- CAS号:80288-49-9
- 英文名:3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
- 中文名:呋喃茶碱
- CBNumber:CB2360403
- 分子式:C12H12N4O3
- 分子量:260.25
- MOL File:80288-49-9.mol
呋喃茶碱化学性质
- 熔点 :>162°C (dec.)
- 沸点 :543.6±60.0 °C(Predicted)
- 密度 :1.443±0.06 g/cm3(Predicted)
- 储存条件 :2-8°C(protect from light)
- 溶解度 :ethanol: 0.33 mg/mL
- 形态 :solid
- 酸度系数(pKa) :8.62±0.70(Predicted)
- 颜色 :white
- InChIKey :KGQZGCIVHYLPBH-UHFFFAOYSA-N
安全信息
- WGK Germany :3
呋喃茶碱性质、用途与生产工艺
- 生物活性 Furafylline 是一种有效且有选择性的人细胞色素 P450IA2 抑制剂，其 IC50 值为 0.07 μM。
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靶点
IC50: 0.07 μM (human cytochrome P450IA2)
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体内研究
Furafylline is a potent and selective inhibitor of human cytochrome P450IA2 with an IC 50 of 0.07 μM in kinase experiment. Furafylline is a methylxanthine derivative that is introduced as a long-acting replacement for theophylline in the treatment of asthma. Administration of Furafylline is associated with an elevation in plasma levels of caffeine, due to inhibition of caffeine oxidation, a reaction catalysed by one or more hydrocarbon-inducible isoenzymes of P450. Furafylline has either very little or no effect on human monooxygenase activities catalysed by other isoenzymes of P450, including P4501ID1, P4501IC, P450IIIA.
呋喃茶碱上下游产品信息
上游原料
下游产品
呋喃茶碱 试剂级价格
- 更新日期：2024/11/08
- 产品编号：HY-107204
- 产品名称：呋喃茶碱 Furafylline
- CAS编号：80288-49-9
- 包装：5mg
- 价格：2180元
- 更新日期：2024/11/08
- 产品编号：HY-107204
- 产品名称：呋喃茶碱 Furafylline
- CAS编号：80288-49-9
- 包装：10mg
- 价格：3270元
呋喃茶碱生产厂家
- 公司名称：Pharmaffiliates Analytics and Synthetics P. Ltd
- 联系电话：--
- 电子邮件：mktg@pharmaffiliates.com
- 国家：印度
- 产品数：6739
- 优势度：58
- 公司名称：CLEARSYNTH LABS LTD.
- 联系电话：--
- 电子邮件：sales@clearsynth.com
- 国家：印度
- 产品数：6257
- 优势度：58
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