红藻氨酸

红藻氨酸化学性质

熔点 :253-254 C
比旋光度 :D24 -14.8° (c = 1.01)
沸点 :353.22°C (rough estimate)
密度 :1.2177 (rough estimate)
折射率 :1.4368 (estimate)
储存条件 :Keep in dark place,Sealed in dry,2-8°C
溶解度 :H₂O: soluble
形态 :White to off-white solid.
酸度系数(pKa) :2.03±0.60(Predicted)
颜色 :White
旋光性 (optical activity) :-14.824 (H2O)
水溶解性 :Soluble to 25 mM in water
稳定性 :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
InChI :InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
InChIKey :VLSMHEGGTFMBBZ-OOZYFLPDSA-N
SMILES :N1C[C@H](C(C)=C)[C@H](CC(O)=O)[C@H]1C(O)=O
EPA化学物质信息 :3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S,3S,4S)- (487-79-6)

安全信息

红藻氨酸性质、用途与生产工艺

生物活性 Kainic acid 是 CNS 中兴奋性氨基酸受体亚型的有效激动剂。
体内研究

Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. HO-I levels are significantly enhanced one, three and seven days after i.c.v, injection of Kainic acid. One day after i.c.v, injection of Kainic acid, the HO-I protein level reaches a maximum and then decreases, but is still significantly enhanced versus the vehicle-injected group. After i.c.v. injection of Kainic acid, HO-I-immunoreactivity is strongly induced not only in the CA3 but also widely in the whole hippocampus.

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