BIOLIMUS A9
- CAS号:851536-75-9
- 英文名:UMiroliMus
- 中文名:BIOLIMUS A9
- CBNumber:CB22470849
- 分子式:C55H87NO14
- 分子量:986.28
- MOL File:851536-75-9.mol
- 沸点 :991.0±75.0 °C(Predicted)
- 密度 :1.15±0.1 g/cm3(Predicted)
- 储存条件 :Store at -20°C
- 溶解度 :DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- 形态 :A solid
- 酸度系数(pKa) :10.40±0.70(Predicted)
- 颜色 :White to light yellow
BIOLIMUS A9性质、用途与生产工艺
- 生物活性 Umirolimus 是一种大环三烯内酯 Rapamycin 的衍生物，是一种强大的免疫抑制剂和抗炎剂。Umirolimus 具有高度的亲脂性，可用做药物洗脱支架。
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体外研究
Umirolimus is a macrocyclic triene lactone, developed with pharmacological properties specifically tailored for localized drug delivery. Umirolimus can be used drug-eluting stent (DES) applications. Owing to its enhanced lipophilicity,it is strongly attracted to binding sites within the vessel wall and small, tortuous vessels, and contributing to cellular absorption and sustained distribution in the vessel wall surrounding the stent.
Umirolimus prevents progression of the cell cycle in G1 phase by inhibiting IL-2/mTOR-mediated P70-KD S6 protein kinase activation. Umirolimus inhibits T-cell growth, as well as smooth muscle cell growth. -
体内研究
The elimination half-life of Umirolimus is approximately 25 h in whole blood.
- 更新日期：2024/08/19
- 产品编号：HY-122402
- 产品名称：Umirolimus
- CAS编号：
- 包装：1 mg
- 价格：1363元
- 更新日期：2024/08/19
- 产品编号：HY-122402
- 产品名称：BIOLIMUS A9 Umirolimus
- CAS编号：851536-75-9
- 包装：5mg
- 价格：3000元
- 公司名称：CLEARSYNTH LABS LTD.
- 联系电话：--
- 电子邮件：sales@clearsynth.com
- 国家：印度
- 产品数：6351
- 优势度：58
