黑色素聚集激素肽
- CAS号:87218-84-6
- 英文名:MELANIN CONCENTRATING HORMONE, SALMON
- 中文名:黑色素聚集激素肽
- CBNumber:CB1314540
- 分子式:C89H139N27O24S4
- 分子量:2099.5
- MOL File:87218-84-6.mol
- 密度 :1.52±0.1 g/cm3(Predicted)
- 储存条件 :−20°C
- 溶解度 :Soluble in DMSO
- 形态 :Solid
- 颜色 :White to off-white
- 安全说明 :22-24/25
- WGK Germany :3
黑色素聚集激素肽性质、用途与生产工艺
- 生物活性 Melanin Concentrating Hormone, salmon是最初在硬骨鱼的垂体中发现的19个氨基酸组成的神经肽，它调节食物摄入，能量平衡，睡眠状态和心血管系统。 Melanin-concentrating hormone是 SLC-1/GPR24 和 MCHR2 的配体。
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靶点
SLC-1/GPR24, MCHR2
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体外研究
An orphan G protein-coupled receptor (SLC-1/GPR24) has been identified as a receptor for MCH (MCHR1). MCHR2 has higher protein sequence homology to MCHR1 than any other G protein-coupled receptor. MCHR2 is specifically activated by nanomolar concentrations of MCH, binds to MCH with high affinity, and signals through Gq protein.
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体内研究
Melanin Concentrating Hormone stimulates appetite. Continuous infusion of Melanin Concentrating Hormone into the ventricular system increases food intake for 7-8 days. Intracerebroventricular infusion of Melanin Concentrating Hormone (10 μg/day) causes a slight but significant increase in body weight in mice maintained on the regular diet. Chronic stimulation of the brain Melanin Concentrating Hormone system could cause obesity in mice.
- 更新日期：2024/11/08
- 产品编号：HY-P1525
- 产品名称：Melanin Concentrating Hormone, salmon
- CAS编号：
- 包装：1 mg
- 价格：900元
- 更新日期：2024/11/08
- 产品编号：HY-P1525
- 产品名称：Melanin Concentrating Hormone, salmon
- CAS编号：
- 包装：5 mg
- 价格：2300元
- 公司名称：SIGMA
- 联系电话：--
- 电子邮件：
- 国家：瑞士
- 产品数：6896
- 优势度：91
