ChemicalBook CAS数据库列表 RELAXIN H2 (HUMAN)
RELAXIN H2 (HUMAN)
- CAS号:99489-94-8
- 英文名:Relaxin H2 (human)
- 中文名:RELAXIN H2 (HUMAN)
- CBNumber:CB12523261
- 分子式:C256H408N74O74S8
- 分子量:5962.95012
- MOL File:99489-94-8.mol
RELAXIN H2 (HUMAN)化学性质
- 储存条件 :Store at -20°C
- 溶解度 :Soluble in DMSO
RELAXIN H2 (HUMAN)性质、用途与生产工艺
- 生物活性 Serelaxin (RLX-030) 是一种靶向 RLN 受体 的重组人松弛素，是一种具有抗纤维化活性的血管活性肽激素。
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体内研究
Serelaxin (0.5 mg/kg per day, subcutaneous administration) produces 20 to 40 ng/mL of circulating hormone, which successfully prevents and reduces fibrosis progression in various experimental models of injury. The doses do not exhibit significant toxicity.
Serelaxin restores endothelial function by increasing nitric oxide (NO)-mediated relaxation but not endothelium-derived hyperpolarisation (EDH).
Animal Model: Six- to 8-week-old male mice (on a 129sv or 129sv×C57B6J background, which were equally sensitive to tissue injury and fibrosis). Dosage: 0.5 mg/kg. Administration: Subcutaneous administration per day for 7 days. Result: Produced 20 to 40 ng/mL of circulating hormone.
RELAXIN H2 (HUMAN)上下游产品信息
上游原料
下游产品
RELAXIN H2 (HUMAN)生产厂家
- 公司名称：Creative Peptides
- 联系电话：
- 电子邮件：info@creative-peptides.com
- 国家：美国
- 产品数：6083
- 优势度：56
- 公司名称：MedChemExpress
- 联系电话：--
- 电子邮件：sales@medchemexpress.com
- 国家：美国
- 产品数：6398
- 优势度：58
