ChemicalBook CAS数据库列表 7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐
- CAS号:76135-31-4
- 英文名:8-OH-DPAT·hydrobromide
- 中文名:7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐
- CBNumber:CB12271735
- 分子式:C16H25NO.BrH
- 分子量:328.29
- MOL File:76135-31-4.mol
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐化学性质
- 熔点 :221.5-222.0 °C
- 储存条件 :Desiccate at +4°C
- 溶解度 :Soluble to 20 mM in water with gentle warming
- 形态 :Powder
- 颜色 :White to off-white
- EPA化学物质信息 :1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1) (76135-31-4)
安全信息
- 海关编码 :2921199990
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐性质、用途与生产工艺
- 生物活性 8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) 是一种有效的，选择性 5-HT1A 激动剂，pIC50 为 8.19。8-Hydroxy-DPAT hydrobromide 对 5-HT1 结合位点的亚型具有近 1000 倍的选择性。
-
靶点
5-HT 1A Receptor
8.19 (pIC 50 )
-
体外研究
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) has no effect on 5-HT 1B binding at concentrations lower than 100 nM.
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体内研究
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide; 32, 56, 80, 100 mg/kg; intramuscularly; 15 min prior to the testing session) of the highest dose significantly interferes with sustained attention and reinforcer efficacy (progressive ratio; PR) performance in the 3,4-methylenedioxymethamphetamine (MDMA)-exposed but not control animals.
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐上下游产品信息
上游原料
下游产品
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐生产厂家
- 公司名称：TORONTO
- 联系电话：--
- 电子邮件：info@trc-canada.com
- 国家：加拿大
- 产品数：6038
- 优势度：71
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