生物活性 靶点 体内研究 (Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE 试剂级价格
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ChemicalBook  CAS数据库列表  (Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE

(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE

生物活性 靶点 体内研究 (Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE 试剂级价格
(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE,2227372-56-5,结构式
(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE
  • CAS号:2227372-56-5
  • 英文名:(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE
  • 中文名:(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE
  • CBNumber:CB1227095
  • 分子式:C10H7Cl4N3
  • 分子量:310.99
  • MOL File:Mol file
(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE化学性质
  • 溶解度 :Soluble to 5 mM in DMSO with gentle warming and to 5 mM in ethanol with gentle warming

(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE性质、用途与生产工艺

  • 生物活性 Loreclezole hydrochloride 是一种抗癫痫化合物，是选择性的 GABAA 受体 的调节剂，是β2 或β3亚单位包含受体的正向变构调节剂。
  • 靶点

    GABA A receptor.

  • 体内研究

    Loreclezole (10, 25, 50 or 75 mg/kg, i.p. 60 min before measurement of seizure threshold ) results in a dosedependent rise in seizure threshold as measured by the dose of pentylenetetrazolrequired to produce a convulsion 60 min later. Loreclezole also has the least effect on loss of muscle tone as measured by the “pull-up” test.

    Animal Model: Adult male Lister Hooded rats.
    Dosage: 10, 25, 50 or 75 mg/kg.
    Administration: IP, 60 min before measurement of seizure threshold.
    Result: Resulted in a dosedependent rise in seizure threshold as measured by the dose of pentylenetetrazolrequired to produce a convulsion 60 min later.
(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE上下游产品信息
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(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE 试剂级价格
  • 更新日期：2024/04/30
  • 产品编号：HY-105272A
  • 产品名称：Loreclezole hydrochloride
  • CAS编号：
  • 包装：10 mg
  • 价格：5789元
(Z)-1-[2-CHLORO-2-(2,4-DICHLOROPHENYL)ETHENYL]-1H-1,2,4-TRIAZOLE HYDROCHLORIDE生产厂家
  • 公司名称：Aladdin Scientific Corporation
  • 联系电话：+1-833-552-7181
  • 电子邮件：sales@aladdinsci.com
  • 国家：美国
  • 产品数：52927
  • 优势度：58
  • 公司名称：Nantong HI-FUTURE Biology Co., Ltd.
  • 联系电话： +undefined18051384581
  • 电子邮件：sales@chemhifuture.com
  • 国家：中国
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  • 优势度：58
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