ChemicalBook CAS数据库列表 3-(溴乙酸酰基)丙酸琥珀酰亚胺酯
3-(溴乙酸酰基)丙酸琥珀酰亚胺酯
- CAS号:57159-62-3
- 英文名:N-SUCCINIMIDYL 3-(BROMOACETAMIDO)PROPIONATE
- 中文名:3-(溴乙酸酰基)丙酸琥珀酰亚胺酯
- CBNumber:CB1123003
- 分子式:C9H11BrN2O5
- 分子量:307.1
- MOL File:57159-62-3.mol
3-(溴乙酸酰基)丙酸琥珀酰亚胺酯化学性质
- 熔点 :93-94°C
- 密度 :1.69±0.1 g/cm3(Predicted)
- 储存条件 :Inert atmosphere,Store in freezer, under -20°C
- 溶解度 :Chloroform (Slightly, Heated), Methanol (Slightly)
- 形态 :Solid
- 酸度系数(pKa) :12.96±0.46(Predicted)
- 颜色 :Off-White to White Waxy
- CAS 数据库 :57159-62-3
安全信息
- 海关编码 :2933998090
3-(溴乙酸酰基)丙酸琥珀酰亚胺酯性质、用途与生产工艺
- 生物活性 N-Succinimidyl 3-(Bromoacetamido)propionate 是一种 PROTAC linker，属于 PEG 类。可用于合成PROTAC分子。N-Succinimidyl 3-(Bromoacetamido)propionate 也是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。
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靶点
PEGs
Alkyl/ether
Cleavable
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体外研究
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
3-(溴乙酸酰基)丙酸琥珀酰亚胺酯上下游产品信息
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3-(溴乙酸酰基)丙酸琥珀酰亚胺酯生产厂家
- 公司名称：TORONTO
- 联系电话：--
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- 国家：加拿大
- 产品数：6038
- 优势度：71
