ChemicalBook CAS数据库列表 LANREOTIDE ACETATE
LANREOTIDE ACETATE
- CAS号:2378114-72-6
- 英文名:Lanreotide acetate
- 中文名:LANREOTIDE ACETATE
- CBNumber:CB05984073
- 分子式:C56H73N11O12S2
- 分子量:1156.39
- MOL File:2378114-72-6.mol
LANREOTIDE ACETATE化学性质
- 形态 :Solid
- 颜色 :White to off-white
LANREOTIDE ACETATE性质、用途与生产工艺
- 生物活性 Lanreotide (Laromustine, Angiopeptin, BIM 23014, Dermopeptin, Ipstyl, ITM-014, Somatulina, Somatuline, Lanreotidum) acetate 是一种天然生长抑素肽的类似物,是生长激素 growth hormone (GH)的生理抑制剂。Lanreotide 也具有抗肿瘤作用。
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体外研究
Lanreotide acetate (BIM 23014 acetate) (24-48 hours; 100 nM; GH3 cells) combines with radiation increasing in apoptotic sub-G1 proportion.
Lanreotide acetate results in a dose-dependent decrease in GH3 cell colony forming units. Lanreotide acetate at doses of 1, 10, 100, and 1000 nM results in cell survival rates of 75, 56, 39 and 27% respectively. The IC50 (50% inhibition of cell growth) was 57 nM.
Lanreotide acetate inhibits GH-secreting pituitary adenoma cell proliferation and hormone release in vitro. -
体内研究
Lanreotide acetate (2.5-10mg/kg; s.c.; daily for 5 days) resluts in tumor growth inhibition.
Animal Model: Male nude mice, 8 weeks old and 20–25 g in body weight (GH3 tumor-bearing nude mice) Dosage: 2.5, 5, 10 mg/kg Administration: Subcutaneous; daily for 5 days Result: Produced tumor growth inhibition.
LANREOTIDE ACETATE上下游产品信息
上游原料
下游产品
LANREOTIDE ACETATE 试剂级价格
- 更新日期:2024/01/16
- 产品编号:P1088
- 产品名称:LANREOTIDE ACETATE Lanreotide acetate
- CAS编号:2378114-72-6
- 包装:5mg
- 价格:892.93元
- 更新日期:2024/01/16
- 产品编号:P1088
- 产品名称:LANREOTIDE ACETATE Lanreotide acetate
- CAS编号:2378114-72-6
- 包装:25mg
- 价格:2678.21元
LANREOTIDE ACETATE生产厂家
- 公司名称:Aladdin Scientific
- 联系电话:+1-+1(833)-552-7181
- 电子邮件:sales@aladdinsci.com
- 国家:美国
- 产品数:57511
- 优势度:58
- 公司名称:TargetMol Chemicals Inc.
- 联系电话:+1-781-999-5354
- 电子邮件:support@targetmol.com
- 国家:美国
- 产品数:19973
- 优势度:58
- 公司名称:MedChemExpress
- 联系电话:--
- 电子邮件:sales@medchemexpress.com
- 国家:美国
- 产品数:6398
- 优势度:58