Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA)
- CAS号:
- 英文名:Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA)
- 中文名:Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA)
- CBNumber:CB05419663
- 分子式:C???H???N??O??S.C?HF?O?
- 分子量:0
- MOL File:Mol file
- 形态 :Solid
- 颜色 :White to off-white
Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA)性质、用途与生产工艺
- 生物活性 Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA) 是一种黑皮质素受体 (melanocortin receptor) 激动剂。
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靶点
Melanocortin receptor
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体外研究
Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH 1-39), a member of the melanocortin family, stimulates production of CS by the adrenals, but melanocortin receptors are also found in the central nervous system (CNS) and on immune cells. ACTH 1-39 protects neurons in vitro from several apoptotic, excitotoxic and inflammation-related insults. The conditioned medium (CM) is prepared from untreated astroglia (AS) cultures and from AS cultures treated with 200 nM ACTH 1-39 for 24 h, washed to remove ACTH 1-39, then incubated for another 24 h in DMEM. In initial experiments, no difference is found in oligodendroglia (OL) viability in the presence of OL definedmediumwith 2% newborn calf serum (NCS) or AS CM (prepared in DMEM with no serum). After 24 h, OL death under each condition varies between 1 and 4%. Similar results for OL viability are obtained with microglia (MG) CM. In subsequent experiments, controls in each experiment consist of OL in defined medium with 2% NCS.
- 更新日期:2024/08/19
- 产品编号:HY-P1211A
- 产品名称:Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA) Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA)
- CAS编号:
- 包装:500μg
- 价格:1600元
- 更新日期:2024/08/19
- 产品编号:HY-P1211A
- 产品名称:Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA) Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA)
- CAS编号:
- 包装:1mg
- 价格:2200元
- 公司名称:天津普西唐生物医药科技有限公司
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