ChemicalBook CAS数据库列表 (Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone
(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone
- CAS号:247167-54-0
- 英文名:(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone
- 中文名:(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone
- CBNumber:CB02727831
- 分子式:C5H2Br2O2
- 分子量:253.88
- MOL File:247167-54-0.mol
(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone化学性质
- 熔点 :97-99 °C
- 沸点 :205.9±40.0 °C(Predicted)
- 密度 :2.650±0.06 g/cm3(Predicted)
- 储存条件 :-20°C
- 溶解度 :Soluble in DMSO
- 形态 :Solid
- 颜色 :White to off-white
- BRN :120928
安全信息
- WGK Germany :3
(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone性质、用途与生产工艺
- 生物活性 Furanone C-30 是一种细菌 (bacterial) 群体感应抑制剂。Furanone C-30 可有效抑制细菌 (如 S. mutans 及其 luxS 突变株) 生物膜形成。
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靶点
Bacterial biofilm
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体外研究
The difference in the OD590 values is statistically significant at concentrations of 2.0 μg/mL and 4.0 μg/mL compared with the control group. Furanone C-30 (2.0 μg/mL and 4.0 μg/mL) can inhibit biofilm formation by S. mutans and its luxS mutant strain, although it does not affect the bacterial growth rate itself.
Cell Viability Assay
Cell Line: Streptococcus mutans UA159 and its luxS mutant strain Concentration: 0.0, 2.0 and 4.0 μg/mL Incubation Time: 24 hours Result: When 2.0 μg/mL was added, the OD590 values for S. mutans and its luxS mutant strain decreased by 42.7% and 40.8%, respectively. When the concentration was increased to 4.0 μg/mL, a decrease of 61.5% and 60.3%, respectively.
(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone上下游产品信息
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(Z-)-4-BroMo-5-(broMoMethylene)-2(5H)-furanone生产厂家
- 公司名称:BOC Sciences
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- 公司名称:Aladdin Scientific
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- 公司名称:MedChemExpress
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