ChemicalBook CAS数据库列表 氢溴酸非诺特罗
氢溴酸非诺特罗
- CAS号:1944-12-3
- 英文名:FENOTEROL HYDROBROMIDE
- 中文名:氢溴酸非诺特罗
- CBNumber:CB0210728
- 分子式:C17H21NO4.BrH
- 分子量:384.27
- MOL File:1944-12-3.mol
氢溴酸非诺特罗化学性质
- 熔点 :226-228°C
- 储存条件 :2-8°C
- 溶解度 :Soluble in water and in ethanol (96 per cent).
- 形态 :Solid
- 颜色 :White to Off-White
安全信息
氢溴酸非诺特罗性质、用途与生产工艺
- 生物活性 Fenoterol hydrobromide (Phenoterol)是fenoterol的氢溴酸盐。Fenoterol是β2 adrenoreceptor激动剂，具有支气管扩张活性。
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靶点
Target Value β2 adrenoreceptor
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体外研究
Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.Western Blot Analysis
Cell Line: THP-1 cells stimulated with AICAR Concentration: 1 μM Incubation Time: Pre-incubated 30 minutes Result: Significantly downregulated the elevated phosphorylation levels of AMPK. -
体内研究
Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.
Animal Model: Male C57BL/6J mice (6 weeks old) with neuropathy Dosage: 0.7 mg/kg Administration: Intraperitoneal injection; twice a day; for 3 weeks Result: Alleviated neuropathic allodynia during chronic treatment. - 用途 校准仪器和装置；评价方法；工作标准；质量保证/质量控制
氢溴酸非诺特罗上下游产品信息
上游原料
下游产品
氢溴酸非诺特罗 试剂级价格
- 更新日期：2024/11/08
- 产品编号：HY-B0976A
- 产品名称：氢溴酸非诺特罗 Fenoterol hydrobromide
- CAS编号：1944-12-3
- 包装：100mg
- 价格：700元
- 更新日期：2024/11/08
- 产品编号：HY-B0976A
- 产品名称：氢溴酸非诺特罗 Fenoterol hydrobromide
- CAS编号：1944-12-3
- 包装：10mM * 1mLin DMSO
- 价格：930元
氢溴酸非诺特罗生产厂家
- 公司名称：Carbone Scientific CO., LTD
- 联系电话：--
- 电子邮件：sales@carbonesci.com
- 国家：英国
- 产品数：6666
- 优势度：30
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