生物活性 靶点 体外研究 体内研究 氢溴酸非诺特罗 试剂级价格
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氢溴酸非诺特罗

氢溴酸非诺特罗,1944-12-3,结构式
氢溴酸非诺特罗
  • CAS号:1944-12-3
  • 英文名:FENOTEROL HYDROBROMIDE
  • 中文名:氢溴酸非诺特罗
  • CBNumber:CB0210728
  • 分子式:C17H21NO4.BrH
  • 分子量:384.27
  • MOL File:1944-12-3.mol
氢溴酸非诺特罗化学性质
  • 熔点 :226-228°C
  • 储存条件 :2-8°C
  • 溶解度 :Soluble in water and in ethanol (96 per cent).
  • 形态 :Solid
  • 颜色 :White to Off-White
安全信息
  • 危险品标志 :Xn
  • 危险类别码 :22
  • 安全说明 :36
  • 危险品运输编号 :3249
  • WGK Germany :3
  • RTECS号 :DO1500000
  • 危险等级 :6.1(b)
  • 包装类别 :III
  • 海关编码 :29225090
  • 毒性 :LD50 in mice (mg/kg): 1100 s.c.; 1990 orally (Goldenthal)

氢溴酸非诺特罗性质、用途与生产工艺

  • 生物活性 Fenoterol hydrobromide (Phenoterol)是fenoterol的氢溴酸盐。Fenoterol是β2 adrenoreceptor激动剂,具有支气管扩张活性。
  • 靶点
    TargetValue
    β2 adrenoreceptor
    ()
  • 体外研究

    Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
    Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
    Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.

    Western Blot Analysis

    Cell Line: THP-1 cells stimulated with AICAR
    Concentration: 1 μM
    Incubation Time: Pre-incubated 30 minutes
    Result: Significantly downregulated the elevated phosphorylation levels of AMPK.
  • 体内研究

    Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.

    Animal Model: Male C57BL/6J mice (6 weeks old) with neuropathy
    Dosage: 0.7 mg/kg
    Administration: Intraperitoneal injection; twice a day; for 3 weeks
    Result: Alleviated neuropathic allodynia during chronic treatment.
  • 用途  校准仪器和装置;评价方法;工作标准;质量保证/质量控制
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氢溴酸非诺特罗 试剂级价格
  • 更新日期:2024/11/08
  • 产品编号:HY-B0976A
  • 产品名称:氢溴酸非诺特罗 Fenoterol hydrobromide
  • CAS编号:1944-12-3
  • 包装:100mg
  • 价格:700元
  • 更新日期:2024/11/08
  • 产品编号:HY-B0976A
  • 产品名称:氢溴酸非诺特罗 Fenoterol hydrobromide
  • CAS编号:1944-12-3
  • 包装:10mM * 1mLin DMSO
  • 价格:930元
氢溴酸非诺特罗生产厂家
  • 公司名称:ARONIS
  • 联系电话:--
  • 电子邮件:aronis@aronis.ru
  • 国家:俄罗斯
  • 产品数:6592
  • 优势度:60
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