93106-59-3
基本信息
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-, Monohydrochloride (9CI)
物理化学性质
| 储存条件 | -20°C储存 |
| 溶解度 | H2O: 2 mg/mL, clear (Warmed) |
| 形态 | Solid |
| 颜色 | White to off-white |
| 水溶解性 | Water : 7.14 mg/mL (Need ultrasonic) |
| InChI | InChI=1S/C19H22FN3O3.ClH/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12;/h9-12H,2-8H2,1H3,(H,25,26);1H |
| InChIKey | PZJWYUDBXNNVLZ-UHFFFAOYSA-N |
| SMILES | N1(C2CC2)C2=C(C=C(F)C(N3CCN(CC)CC3)=C2)C(=O)C(C(O)=O)=C1.[H]Cl |
安全数据
| 危险性符号(GHS) |   GHS08,GHS07 |
| 警示词 | 危险 |
| 危险性描述 | H302,H317,H334 |
| 防范说明 | P261-P264-P272-P280-P301+P312-P302+P352 |
盐酸恩诺沙星价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-B0502AR | 盐酸恩诺沙星 Enrofloxacin monohydrochloride (Standard) | 93106-59-3 | 10 mg | 340元 |
| 2026/09/15 | HY-B0502AR | 盐酸恩诺沙星 Enrofloxacin monohydrochloride (Standard) | 93106-59-3 | 25 mg | 660元 |
| 2026/09/15 | HY-B0502AR | 盐酸恩诺沙星 Enrofloxacin monohydrochloride (Standard) | 93106-59-3 | 50 mg | 1000元 |
常见问题列表
MIC90: 0.312 μg/mL ( Mycoplasma bovis )
Mycoplasma bovis is a worldwide pathogen, causative agent of pneumonia, mastitis, arthritis, and a variety of other symptoms in cattle. The antibiotic susceptibility profiles of the Hungarian strains are consistent within the tested group of fluoroquinolones. Three isolates (MYC44, MYC45 and MYC46) have high MIC values (≥10 μg/mL) to Enrofloxacin, while the rest of the strains are inhibited by Enrofloxacin with MICs ≤0.312 or 0.625 μg/mL.
Mice (n=80) undergo transient middle cerebral artery occlusion (MCAo) with reperfusion after 60 minutes. After MCAo, animals are randomly assigned to receive either a daily preventive medication (n=26, Enrofloxacin) starting at the day of MCAo or a therapeutic medication (n=25; Enrofloxacin) after diagnosis of lung infection. Standard treatment started immediately after the appearance of clinical signs (general health score>6) usually between day 4 and 6 after stroke. Both, preventive and standard antibiotic treatment using Enrofloxacin improve survival in a similar way compared with placebo treatment.