876371-13-0
英文名称
BI-4834
CAS
876371-13-0
分子式
C32H47N7O4
分子量
593.76
MOL 文件
876371-13-0.mol
结构式
基本信息
英文别名
BI-4834
应用领域
用途一
BI-4834 is a potent and selective Polo-like kinase 1 (PLK1) inhibitor. BI-4834 is also analogue (or Me-Too) of BI-2536. In vitro test shows that BI 4834 inhibits PLK1 with IC50=7.6 nm, but with higher selectivity over the related enzyme PLK3 (IC50 198.4 nm) as BI-2536.