76970-77-9
中文名称
化合物 CANTHARIDIN IMIDE
英文名称
hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione
CAS
76970-77-9
分子式
C10H13NO3
分子量
195.22
MOL 文件
76970-77-9.mol
结构式
基本信息
中文别名
化合物 CANTHARIDIN IMIDE
英文别名
Cantharidin imide
hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, hexahydro-3A,7A-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-
hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, hexahydro-3A,7A-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-
物理化学性质
| 熔点 | 205-206 °C(Solvent: Ethanol) |
| 沸点 | 353.647±35.00 °C(Press: 760.00 Torr)(predicted) |
| 密度 | 1.310±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| 酸度系数(pKa) | 11.185±0.60(predicted) |
应用领域
用途一
Cantharidin imide is a PP1/2A inhibitor found in Canarthis vesicatoria. It inhibits proliferation of colorectal cancer cells, increases MCP-1, IL-6, and IL-β levels, and inhibits differentiation and resorptive activity of osteoclasts. This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
安全数据
| 海关编码 | 2925190090 |