73326-98-4
中文名称
5氢-吡啶并[4,3-B]咔唑-5,11(6氢)-二酮
英文名称
5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione
CAS
73326-98-4
分子式
C15H8N2O2
分子量
248.24
MOL 文件
73326-98-4.mol
结构式
基本信息
中文别名
5氢-吡啶并[4,3-B]咔唑-5,11(6氢)-二酮
英文别名
5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione
所属类别
医药中间体：原料药中间体
应用领域
用途一
Ellipticine quinone, also known as NSC-383230, is a Drp1 inhibitor. rpitor1 and Drpitor1a inhibited the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1. Ellipticine quinone showed greater potency than the current std. Drp1 GTPase inhibitor, mdivi-?1, (IC50 for mitochondrial fragmentation are (0.06, and 10 μM, resp.)?. Ellipticine quinone suppressed lung cancer tumor growth in a mouse xenograft model. Ellipticine quinone also inhibited mitochondrial ROS prodn., prevented mitochondrial fission, and improved right ventricular diastolic dysfunction during IR injury.
供应商信息 更多
TargetMol中国（陶术生物）
联系电话：
15002134094
产品介绍：
中文名称：化合物 Ellipticine quinone
英文名称：Ellipticine quinone
CAS：73326-98-4
包装信息：50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500