688737-95-3
英文名称
TP-110
CAS
688737-95-3
分子式
C37H41N3O6
分子量
623.74
MOL 文件
688737-95-3.mol
结构式
基本信息
英文别名
TP-110
应用领域
用途一
TP-110 is a new proteasome inhibitor, which shows potent growth inhibition in various tumor cell lines. Treatment with TP-110 for 24 h in vitro induced apoptosis in multiple myeloma cell line RPMI8226. TP-110 reduced the intrinsic inhibitor of apoptosis proteins (IAPs), cIAP-1 and XIAP, that suppress executioner caspases.