65321-41-7
中文名称
化合物 T33437
英文名称
MK 761
CAS
65321-41-7
分子式
C13H19N3O2
分子量
249.31
MOL 文件
65321-41-7.mol
结构式
基本信息
中文别名
化合物 T33437
英文别名
MK 761
3-Pyridinecarbonitrile, 2-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, (S)- (9CI)
3-Pyridinecarbonitrile, 2-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, (S)- (9CI)
物理化学性质
| 沸点 | 435.2±45.0 °C(Predicted) |
| 密度 | 1.13±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 13.55±0.20(Predicted) |
| 形态 | Solid |
| 颜色 | Off-white to light yellow |
应用领域
用途一
MK761 is a new class of compound which has beta adrenoceptor antagonist and vasodilating properties in a single molecule. The compound has in vitro beta adrenoceptor blocking activity in the isolated cat heart papillary muscle and isolated rat atria. It is approximately as potent as timolol and pindolol in blocking cardiac and vascular beta adrenergic receptors.