64078-09-7
中文名称
CGP11952
英文名称
CGP 11952
CAS
64078-09-7
分子式
C21H21Cl2N5O2
分子量
446.33
MOL 文件
64078-09-7.mol
结构式
基本信息
中文别名
化合物 T14940
英文别名
CGP 11952
1H-1,2,4-Triazole-3-carboxamide, 1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-5-[(dimethylamino)methyl]-N-ethyl-
1H-1,2,4-Triazole-3-carboxamide, 1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-5-[(dimethylamino)methyl]-N-ethyl-
物理化学性质
| 储存条件 | -20°C储存 |
| 溶解度 | 溶于二甲基亚砜 |
常见问题列表
生物活性
CGP11952 是一种三唑基 Benzaphenon。CGP11952 是一种苯二氮卓类 (benzodiazepine) 衍生物。
靶点
Benzodiazepine
体外研究
CGP11952 (CGP 11952) is a triazolyl-Benzaphenon resembling the benzodiazepines in its pharmacological action. The effects of CGP11952 (CGP 11.952), a triazolyl Benzophenone, on cognitive functioning are assessed by means of a computerized neuropsychological battery. In the first study CGP11952 turns out to have a positive effect on information processing speed, perceptual sensitivity and preciseness of responses. Negative effects are found on reaction time. In the second study this latter effect is less clear. A striking result is the less negative effect on memory consolidation under influence of CGP11952 in comparison with other benzodiazepines.