579511-43-6
中文名称
化合物 T27081
英文名称
CRA 19156
CAS
579511-43-6
分子式
C24H23N3O4
分子量
417.47
MOL 文件
579511-43-6.mol
结构式
应用领域
用途一
CRA-19156 is a potent HDAC8 inhibitor. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from lysines near the N termini of histones. This reaction promotes the condensation of chromatin, leading to repression of transcription. HDAC deregulation has been linked to several types of cancer, suggesting a potential use for HDAC inhibitors in oncology.