57410-31-8

Bts 39542 is a diuretic. The ratio of the excretion of the major cations (sodium plus potassium) to that of the major anion (chloride) after BTS 39542 varied with species. In dogs, Bts 39542 exerts its major effects in the loop of Henle and increases renal blood flow but does not affect glomerular filtration rate.

BTS 39542 是口服有效的钠钾氯共转运蛋白 (Na+ K+ Cl cotransport system) 抑制剂，具有利尿作用，可用于高血压和水肿研究。