28656-91-9
基本信息
AEROPLYSININ
aeroplysinini
(+)-aeroplysinini
(+)-AEROPLYSININ-1
(+)shy-Aeroplysinin-1
Aeroplysinin (Aeroplysinin-1)
AEROPLYSININ, APLYSINA AEROPHOBA
(+)-AEROPLYSININ-1, APLYSINA AEROPHOBA
4-cyclohexadiene-1-acetonitrile,3,5-dibromo-1,6-dihydroxy-4-methoxy-(1s-tr
物理化学性质
| 沸点 | 479.6±45.0 °C(Predicted) |
| 密度 | 2.01±0.1 g/cm3(Predicted) |
| 储存条件 | -20°C储存 |
| 溶解度 | 可溶于甲醇： |
| 酸度系数(pKa) | 10.54±0.70(Predicted) |
| 形态 | 固体 |
| 颜色 | Colorless to off-white |
安全数据
| 海关编码 | 2941900000 |
(+)-AEROPLYSININ-1价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-19827 | (+)-AEROPLYSININ-1 Aeroplysinin 1 | 28656-91-9 | 100 μg | 4140元 |
常见问题列表
|
Bacterial
|
HIV-1 14.6 μM (IC 50 ) |
Apoptosis
|
Aeroplysinin 1 shows anti-proliferative effect against tumor cells (HT-1080, HTC-116, HeLa, THP-1, NOMO-1 and HL-60 cells), with IC
50
s ranging from 2.3 to 17 μM.
Aeroplysinin-1 also exhibits an antiviral activity toward HIV-1 caused by inhibition of its reverse transcriptase activity.
Aeroplysinin 1 inhibits
P. phosphoreum
,
C. wailesii
,
P. minimum
and HIV with IC
50
s of 3.5, 5.6, 7.0 and 14.6 μM.
Aeroplysinin 1 inhibits human endothelial cells (EVLC-2, HMEC, RF-24, and HUVEC cells), with IC
50
s ranging from 2.6 to 4.7 μM.
(+)-Aeroplysinin-1 (0.25-0.5 μM) blocks the EGF-dependent proliferation of both MCF-7 and ZR-75-1 human breast cancer cells and inhibits the ligand-induced endocytosis of the EGF receptor in vitro.