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Polyglutamine is a portion of a protein consisting of a sequence of several glutamine units. A tract typically consists of about 10 to a few hundred such units._x000D_ _x000D_ A multitude of genes, in various eukaryotic species (including humans), contain a number of repetitions of the nucleotide triplet CAG or CAA. When the gene is translated into a protein, each of these triplets gives rise to a glutamine unit, resulting in a polyglutamine tract. Different alleles of such a gene often have different numbers of triplets since the highly repetitive sequence is prone to contraction and expansion.