223671-94-1
中文名称
化合物 UK-356202
英文名称
3-(4-CHLORO-1-GUANIDINOISOQUINOLIN-7-YL)BENZOIC ACID
CAS
223671-94-1
分子式
C17H13ClN4O2
分子量
340.76
MOL 文件
223671-94-1.mol
结构式
基本信息
中文别名
UK-356202-2
化合物 UK-356202
化合物 UK-356202
英文别名
UK-356202
3-(4-CHLORO-1-GUANIDINOISOQUINOLIN-7-YL)BENZOIC ACID
3-[4-chloro-1-(diaminomethylideneamino)isoquinolin-7-yl]benzoic acid
3-(4-CHLORO-1-GUANIDINOISOQUINOLIN-7-YL)BENZOIC ACID
3-[4-chloro-1-(diaminomethylideneamino)isoquinolin-7-yl]benzoic acid
物理化学性质
| 熔点 | >300 °C |
| 沸点 | 596.9±60.0 °C(Predicted) |
| 密度 | 1.49±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 3.99±0.10(Predicted) |
应用领域
用途一
UK-356,202 is a potent and selective urokinase-type plasminogen activator (Ki = 37 nM). Urokinase plasminogen activator (uPA, urokinase) is a trypsinlike serine protease and a therapeutical target for many cancer types, including breast, ovarian, and pancreatic cancer. uPA is a valuable oncology target.