216167-92-9
基本信息
AGIX 4207
Acetic acid,2-[4-[[1-[[3,5-bis(1,1-diMethylethyl)-4-hydroxyphenyl]thio]-1-Methylethyl]thio]-2,6-bis(1,1-diMethylethyl)phenoxy]-
物理化学性质
| 熔点 | 164-165 °C |
| 沸点 | 622.6±55.0 °C(Predicted) |
| 密度 | 1.11±0.1 g/cm3(Predicted) |
| 储存条件 | -20°C储存 |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 3.23±0.10(Predicted) |
| 形态 | Solid |
| 颜色 | White to yellow |
216167-92-9价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-14916 | Camobucol | 216167-92-9 | 1 mg | 1818元 |
| 2026/09/15 | HY-14916 | 216167-92-9 Camobucol | 216167-92-9 | 5mg | 4000元 |
| 2026/09/15 | HY-14916 | Camobucol | 216167-92-9 | 10 mM * 1 mLin DMSO | 5059元 |
常见问题列表
Camobucol exhibits potent antioxidant activity toward lipid peroxides in vitro and displays enhanced cellular uptake. Camobucol selectively inhibits tumor necrosis factor (TNF)-α-inducible levels of the redox-sensitive genes, vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1, with less inhibition of E-selectin, and no effect on intracellular adhesion molecule-1 expression in endothelial cells. In addition, Camobucol inhibits cytokine-induced levels of monocyte chemoattractant protein-1, interleukin (IL)-6, and IL-8 from endothelial cells and human fibroblast-like synoviocytes as well as lipopolysaccharide-induced release of TNF-α, IL-1β, and IL-6 from human peripheral blood mononuclear cells. Camobucol does not inhibit TNF-α-induced nuclear translocation of nuclear factor of the κ-enhancer in B cells (NF-κB), suggesting that the mechanism of action is independent of this redox-sensitive transcription factor.