16670-83-0
中文名称
(+)-(2S,[2Α,6Α,11R])-1,2,3,4,5,6-六氢-6,11-二甲基-2,6-亚甲基-3-喷他佐辛-8-醇
英文名称
(+)-NORMETAZOCINE N-DEMETHYLATED ANALOG
CAS
16670-83-0
分子式
C14H19NO
分子量
217.31
MOL 文件
16670-83-0.mol
结构式
基本信息
中文别名
(+)-去甲美他佐辛
(+)-(2S,[2Α,6Α,11R])-1,2,3,4,5,6-六氢-6,11-二甲基-2,6-亚甲基-3-喷他佐辛-8-醇
(+)-(2S,[2Α,6Α,11R])-1,2,3,4,5,6-六氢-6,11-二甲基-2,6-亚甲基-3-喷他佐辛-8-醇
英文别名
(+)-Normetazocine
(+)-NORMETAZOCINE N-DEMETHYLATED ANALOG
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2S,6S,11S)-
(+)-(2S,[2α,6α,11R])-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol
(+)-NORMETAZOCINE N-DEMETHYLATED ANALOG
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2S,6S,11S)-
(+)-(2S,[2α,6α,11R])-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol
物理化学性质
| 熔点 | 260-262 °C |
| 沸点 | 355.8±42.0 °C(Predicted) |
| 密度 | 1.088±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 9.79±0.60(Predicted) |
| 形态 | neat |
应用领域
用途1
(+)-Normetazocine is an analgesia-antagonistic active compound. It acts as both an agonist and antagonist, however shows less effects than (-)-Normetazocine (N721900). Used in the synthesis of BNIT, a
selective inhibitor of the opioid receptor 蟽1.
安全数据
| WGK Germany | 3 |