1374647-07-0
中文名称
化合物 T24371
英文名称
L-Phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-4-benzoyl-N-5-hexyn-1-yl-
CAS
1374647-07-0
分子式
C52H64N4O7
分子量
857.09
MOL 文件
1374647-07-0.mol
结构式
基本信息
中文别名
化合物 T24371
英文别名
L458BPyne
L458-BPyne
L458 BPyne
L-Phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-4-benzoyl-N-5-hexyn-1-yl-
L458-BPyne
L458 BPyne
L-Phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-4-benzoyl-N-5-hexyn-1-yl-
应用领域
用途一
L458-BPyne is a γ-secretase modulator photoaffinity probe. It acts by identifying distinct allosteric binding sites on presenilin that can be exploited to reduce levels of pathogenic Aβ species.