130849-58-0
基本信息
Thiazolidine, 3-[(2,3-dihydro-1H-inden-2-yl)acetyl]-4-(1-pyrrolidinylcarbonyl)-, (4R)- (9CI)
物理化学性质
沸点 | 588.8±50.0 °C(Predicted) |
密度 | 1.265±0.06 g/cm3(Predicted) |
储存条件 | -20°C储存 |
溶解度 | DMSO: 250 mg/mL (725.75 mM) |
酸度系数(pKa) | -0.84±0.20(Predicted) |
形态 | Solid |
颜色 | White to off-white |
130849-58-0价格(试剂级)
报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2024/11/08 | HY-19123 | 130849-58-0 Z-321 | 130849-58-0 | 1mg | 2600元 |
2024/11/08 | HY-19123 | 130849-58-0 Z-321 | 130849-58-0 | 5mg | 6000元 |
2024/08/19 | HY-19123 | 130849-58-0 Z-321 | 130849-58-0 | 10mg | 7200元 |
常见问题列表
PEP
Z-321 is a prolylendopeptidase (PEP) inhibitor. In the 100 or 200 mg/kg Z-321-treated groups, mean lordosis quotient (LQ) decreases after administration. However, there is no statistical difference among the values before and after. In contrast, the mean LQ in the 300 mg/kg Z-321-treated females is lower than that before injection (P<0.005). Furthermore, when compare to that in the vehicle-treated control group, mean LQ is also significantly lower (p<0.05). The incidence of soliciting behavior decreases after treatment with 300 mg/kg Z-321, when compare to that before treatment, but there is no statistical difference. The present study also demonstrates that 300 mg/kg Z-321 is effective in inhibiting lordosis behavior without disturbance of locomotor activity.