129551-91-3
英文名称
JM 221
CAS
129551-91-3
分子式
C8H14Cl2O4Pt.C6H13N.H3N
分子量
556.387
MOL 文件
129551-91-3.mol
结构式
基本信息
英文别名
JM 221
应用领域
用途一
JM-221 is a novel platinum(IV) dicarboxylate complex exhibiting enhanced cytotoxicity in human ovarian carcinoma cell line when compared to Cisplatin. Comparison with platinum accumulation from Cisplatin suggests that the increased cytotoxicity of JM-221 may be related_x000D_
to increased accumulation within the cell. JM-221 is more lipophilic than Cisplatin, which may account for improved uptake in Cisplatin resistant cells.