127-35-5
中文名称
非那佐辛
英文名称
phenazocine
CAS
127-35-5
分子式
C22H27NO
分子量
321.46
MOL 文件
127-35-5.mol
结构式
基本信息
中文别名
苯吖啶
非那佐辛
非那佐辛
英文别名
SKF-6574
Prinadol
phenazocine
Phenobenzorphan
Phenethylazocine
ZQHYKVKNPWDQSL-NKDCDXMNSA-N
2'-Hydroxy-5,9-diMethyl-2-phenethyl-6,7-benzoMorphan
1,2,3,4,5,6-Hexahydro-6,11-diMethyl-3-phenethyl-2,6-Methano-3-benzazocin-8-ol
1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-phenylethyl)-2,6-methano-3-benzazocin-8-ol
Prinadol
phenazocine
Phenobenzorphan
Phenethylazocine
ZQHYKVKNPWDQSL-NKDCDXMNSA-N
2'-Hydroxy-5,9-diMethyl-2-phenethyl-6,7-benzoMorphan
1,2,3,4,5,6-Hexahydro-6,11-diMethyl-3-phenethyl-2,6-Methano-3-benzazocin-8-ol
1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-phenylethyl)-2,6-methano-3-benzazocin-8-ol
物理化学性质
| 熔点 | 181 °C |
| 沸点 | 460.995±45.00 °C(Press: 760.00 Torr)(predicted) |
| 密度 | 1.097±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| 酸度系数(pKa) | pKa 8.50(50% aq EtOH) (Uncertain) |
应用领域
用途1
Phenazocine is an opioid analgesic drug related to Pentazocine (P274300) and has a similar profile of effects. The use of Phenazocine results in analgesia and euphoria and in some cases dysphoria and hallucinations at high doses, most likely due to action at κ-opioid and σ receptors. Phenazocine is a much more potent analgesic than morphine with about 4 times the potency and very little side effec ts making it a better treatment option for biliary or pancreatic pain. Controlled Substance.
安全数据
| DEA Controlled Substances | CSCN: 9715 CSA SCH: Schedule II NARC: Yes |