1221418-42-3

SAR-629 is a MGL inhibitor or 2-AG degradation inhibitor. Monoglyceride lipase (MGL) is a serine hydrolase that hydrolyses 2-arachidonoylglycerol (2-AG) into arachidonic acid and glycerol. 2-AG is an endogenous ligand of cannabinoid receptors, involved in various physiological processes in the brain.

SAR629 是一种有效的甘油单酯脂肪酶 (MGL) 共价抑制剂。SAR629 还抑制 2-Arachidonoylglycerol (2-AG) 降解。