113158-34-2
基本信息
物理化学性质
| 熔点 | >280 °C (decomp) |
| 储存条件 | Store at RT |
| 溶解度 | Soluble to 25 mM in water with gentle warming and to 25 mM in DMSO |
| 形态 | 粉末 |
| 颜色 | Light yellow to gray |
| InChIKey | JOJPJLHRMGPDPV-LZQROVCBSA-N |
| SMILES | Cl[H].Cl[H].Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)c6[nH]c7[C@@H]8Oc9c(O)ccc%10C[C@H]%11N(CC[C@@]8(c9%10)[C@@]%11(O)Cc7c6C[C@@]35O)CC%12CC%12)CC%13CC%13 |
安全数据
| WGK Germany | WGK 3 |
| 存储类别 | 11 - Combustible Solids |
Norbinaltorphimine Dihydrochloride价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-100903 | Norbinaltorphimine Dihydrochloride Norbinaltorphimine dihydrochloride | 113158-34-2 | 5 mg | 950元 |
| 2026/09/15 | HY-100903 | Norbinaltorphimine Dihydrochloride Norbinaltorphimine dihydrochloride | 113158-34-2 | 10 mg | 1500元 |
| 2026/09/15 | HY-100903 | Norbinaltorphimine Dihydrochloride Norbinaltorphimine dihydrochloride | 113158-34-2 | 10 mM * 1 mL in DMSO | 1536元 |
常见问题列表
κ opioid receptor
Norbinaltorphimine reversibly antagonize the effects of κ agonists with pA2 values of 10.2-10.4. Norbinaltorphimine is much less potent as an antagonist at μ and δ receptors, pA2 values are 7.4-7.6 and 7.6-7.8, respectively.
Norbinaltorphimine has weak and inconsistent effects on THC-induced taste avoidance in adolescent rats in that Norbinaltorphimine both attenuates and strengthens taste avoidance dependent on dose and trial. Norbinaltorphimine has limited impact on the final one-bottle avoidance and no effects on the two-bottle preference test. Interestingly, Norbinaltorphimine has no effect on THC-induced taste avoidance in adult rats as well. Norbinaltorphimine pretreatment significantly attenuates stress-induced reinstatement of nicotine-CPP, but has no effect on nicotine-primed reinstatement.