107431-28-7
中文名称
化合物 ENADOLINE (FREE BASE)
英文名称
enadoline
CAS
107431-28-7
分子式
C24H32N2O3
分子量
396.522
MOL 文件
107431-28-7.mol
结构式
基本信息
中文别名
化合物 ENADOLINE (FREE BASE)
英文别名
Cam 569
Pd 129289
N-Methyl-N-(7-(1-pyrolidinyl)-1-oxaspiro(4,5)dec-8-yl)-4-benzofuranacetamide
4-Benzofuranacetamide, N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-
Pd 129289
N-Methyl-N-(7-(1-pyrolidinyl)-1-oxaspiro(4,5)dec-8-yl)-4-benzofuranacetamide
4-Benzofuranacetamide, N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-
应用领域
用途一
Enadoline (Free Base) is a kappa-opioid receptor agonist; PD 129290 (CAM 570; CI 977) is the S,S(-)-enantiomer; PD 129289 (CAM 569) is the corresponding R,R(+)-enantiomer. In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a κ-opioid agonist. There was mention of its potential in treating comatose head injury or stroke victims, where that type of side effect would be immaterial.
常见问题列表
概述
(Rac)-Enadoline ((Rac)-CI-977 free base) 是一种选择性 K-阿片受体激动剂，能够立体选择性地拮抗由 N-甲基-DL-天冬氨酸缓慢静脉注射引起的小鼠阵挛性癫痫发作。
供应商信息 更多
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产品介绍：
中文名称：化合物 Enadoline Free Base
英文名称：Enadoline Free Base
CAS：107431-28-7
包装信息：25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500