103295-92-7
中文名称
化合物 T28562
英文名称
Ro 18-3981
CAS
103295-92-7
MOL 文件
103295-92-7.mol
结构式
基本信息
中文别名
化合物 T28562
英文别名
Ro 18-3981
1,4-Dihydro-2,6-dimethyl-5-[[[(1-methylethyl)amino]sulfonyl]acetyl]-4-(3-nitrophenyl)-3-pyridinecarboxylic acid 2-propoxyethyl ester
1,4-Dihydro-2,6-dimethyl-5-[[[(1-methylethyl)amino]sulfonyl]acetyl]-4-(3-nitrophenyl)-3-pyridinecarboxylic acid 2-propoxyethyl ester
应用领域
用途一
Ro 18-3981 inhibits myocardial Ca2+ channels. The KD value of Ro 18-3981 (1.0 nM) was similar to the IC50 value for blockade of ICa at a Vh of -20 mV (2.3 nM), i.e. at a level of near-maximal depolarization.