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R-(–)-Flecainide is the (R) enantiomer of the antiarrhythmic agent flecainide . R-(–)-Flecainide prevents chloroform-induced ventricular fibrillation in mice (ED₅₀ = 14.5 mg/kg). It also prevents ouabain-induced ectopic ventricular tachycardia in anesthetized dogs.

R-Enantiomer of Flecainide. Antiarrhythmic (class IC)

R-Enantiomer of Flecainide. Antiarrhythmic (class IC).

[1] ELDEN H. BANITT  Richard A N  Jack R Schmid. Resolution of flecainide acetate, N-(2-piperidylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide acetate, and antiarrhythmic properties of the enantiomers[J]. Journal of Medicinal Chemistry, 1986, 29 2: 299-302. DOI: 10.1021/jm00152a021