General Description
A colorless liquid with an aromatic odor. May sink or float on water.
Reactivity Profile
2-FLUOROTOLUENE(95-52-3) is of generally low reactivity. Reacts with strong oxidizing agents and strong reducing agents. Also may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides [USCG, 1999].
Air & Water Reactions
Highly flammable. Insoluble in water.
Health Hazard
Inhalation of vapor may cause respiratory irritation. Prolonged and repeated vapor exposures may produce systemic toxic effects.
Chemical Properties
clear colorless to slightly yellow liquid
Uses
It is employed in organic synthesis.
Synthesis
The halogen exchange method reacts aromatic compounds with alkali metal fluorides (e.g., CsF and KF, etc.) and substituent groups, allowing the fluorine atom to replace other halogen groups (e.g., chlorine). The reaction method of halogen exchange between
Purification Methods
Dry o-fluorotoluene with P2O5 or CaSO4 and fractionally distil it through a silvered vacuum-jacketed glass column with 1/8th-in glass helices. A high reflux ratio is necessary because of the closeness of the boiling points of the o-, m-and p-isomers [Potter & Saylor J Am Chem Soc 37 90 1951]. [Beilstein 5 H 290, 5 III 676, 5 IV 799.]
