GSK8062 is a farnesoid X receptor (FXR) agonist with activity that improves compound development parameters. Analog 1c of GSK8062 showed a reduction in weight gain and serum glucose levels[1].
References
[1] Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene DOI:10.1016/j.bmcl.2010.12.089
