938444-93-0

Synonyms

D-106669 N-Ethyl-N'-[3-[(4-methylphenyl)amino]pyrido[2,3-b]pyrazin-6-yl]urea Urea, N-ethyl-N'-[3-[(4-methylphenyl)amino]pyrido[2,3-b]pyrazin-6-yl]-

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Chemical Properties

D-106669 (comppun 150) is a potent inhibitor of PI3Kα, with the IC50 of 0.129 μM. D-106669 plays an important role in cancer research[1][2].

PI3Kα: 0.129 μM (IC₅₀)

[1] Seipelt Irene, et al. Preparation of pyridopyrazines as kinase modulators. United States, US20070123494 A1 2007-05-31.

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