Shanghai T&W Pharmaceutical Co., Ltd.
Telephone+86 21 61551611
Websitehttp://www.trustwe.com
Nanjing YakeLun Pharmaceutical Co., Ltd.
Telephone025-66096098 3165145969
Websitehttp://www.accoronpharm.com/
Shanghai Haohong Pharmaceutical Co., Ltd.
Telephone4008210725 4008210725
Websitehttps://www.leyan.com/
Yuzhou Enthalpy Carbon Pharmaceutical Technology Co. LTD
Telephone19963477321; 19963477321
Websitehttps://www.chemicalbook.com/ShowSupplierProductsList827404/0.htm
Hangzhou Taorui Biotechnology Co., Ltd
Telephone4000-360-990 15268198094
Websitehttp://www.torreybio.com/
SINO High Goal Chemical Technology Co., Ltd.
Telephone021-57646680 18306277365
Websitehttp://www.chembiobanksh.com/
Zhuhai Aobokai Biomedical Technology Co., Ltd.
Telephone400-0628126
Websitehttp://www.aobchem.com.cn/
Shanghai Yanbang Pharmaceutical Technology Co., Ltd
Telephone 15618536883
Websitehttps://www.chemicalbook.com/ShowSupplierProductsList614748/0.htm
Yantai Shengkailun Chemical Technology Co., Ltd.
Telephone 13356901049
Websitehttps://www.sklnchem.cn
Jilin Chinese Academy of Sciences-yanshen Technology
Telephone 18143011203
Websitehttp://www.chemextension.com/
Open to the atmosphere, 4-bromoanisole (1.87 g, 10 mmol), o-tolylboronic acid (1.50 g, 11 mmol), KF (spray dried, dried in an oven overnight prior to use, 1.92 g, 33 mmol), and THF (10 mL) were added to a 100-ml round-bottomed Schlenk flflask equipped with a stir bar. The reaction system was flflushed with argon for about 5 min. P(t-Bu)3 (1.9 × 10–4 M stock solution in THF; 2.31 mL, 5.0 × 10–5 mmol) and Pd2(dba)3 (2.16 × 10–5 M stock solution in THF; 2.31 mL, 5.0 × 10–5 mmol) in THF were added sequentially. After 48 h at room temperature, the reaction mixture was diluted with ether or EtOAc, fifiltered through a pad of silica gel with copious washings, and then concentrated. The crude product was then purifified via column chromatography eluting with 5% ether in hexane to yield 1.94 g (98%) of 4-methoxy-2´-methylbiphenyl as a colorless liquid.
;