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FPMINT is a potent, irreversible and non-competitive inhibitor of Equilibrative nucleoside transporters (ENTs), which is more selective to ENT2 than to ENT1. FPMINT plays an important role in uridine uptake[1].

FPMINT is a potentirreversible and non-competitive inhibitor of equilibrative nucleoside transporters ENT1 and ENT2. FPMINT is more selective for ENT2 than ENT1.

[1] Renkai Li, et al. Structure-Activity Relationship Studies of 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine (FPMINT) Analogues as Inhibitors of Human Equilibrative Nucleoside Transporters. Front Pharmacol. 2022 Feb 21:13:837555. DOI:10.3389/fphar.2022.837555